Ongoing Research Projects

1. Maternal Antecedents of Adiposity and Studying the Transgenerational role of Hyperglycemia and Insulin (MAASTHI). An Intermediate Fellowship. Hyperglycemia in Pregnancy and risk of chronic diseases. Giridhara R Babu (PI) Wellcome Trust-DBT India Alliance, 07/16/15 to 07/15/20; The aim of this study is to prospectively assess the effects of glucose levels in pregnancy on the risk of adverse infant outcomes, especially in predicting the possible risk markers of later chronic disea
2. Full meal supplementation: Evaluation of Effect in Pregnant and Lactating women (FEEL) Department of Women and Child, Government of Karnataka/UNICEF, 04/01/17-02/28/18,. Giridhara R Babu (PI); The aim of the state level intervention study is to study the impact of hot nutritious meals provided to pregnant women in improving pregnancy and infant.
3. Ambient and Indoor Air Pollution in Pregnancy on the risk of Low birth weight and Ensuing Effects in Infants (APPLE); A cohort study in South India. Giridhara R Babu, Principal Investigator (PI). Department of Science and Technology. 04/01/17-02/28/19. The aim of this study is to prospectively assess the effects of ambient and indoor air pollutant levels in pregnancy on the risk of low birth weight and ensuing obesity in infants.
4. Effect of exposure to ambient Air Pollution during Pregnancy on Infant birth outcomeS (E-APPS)

Details of the Ongoing Research Projects

Maternal Antecedents of Adiposity and Studying the Transgenerational role of Hyperglycemia and Insulin (MAASTHI): a prospective cohort study. Funded by Wellcome Trust DBT India Alliance: Link1 Link2 Link3

Accomplishments

1. The knowledge from this study may be extremely important for developing an effective strategy for the control of the obesity-hyperglycaemia epidemic in low-income and middle-income countries. The results from our study can provide insights into the relation of adiposity during infancy and childhood into adult adiposity and Type 2 Diabetes Mellitus (T2DM).
2. We have been able to recruit more than 700 pregnant women. All women have undergone Hb and OGTT (Fasting and 2 Hr PPBS with 75g glucose).
3. Additional funding requests are underway for expansion of the birth cohort and for testing the additional hypotheses.